Gani

While we have considerable information regarding the teratogenic risk associated with prenatal exposure to various antiepileptic drugs (AEDs), we have considerably less information on the impact of exposure to AEDs on behavioral outcomes in children.  Several studies have shown that exposure to valproic acid (Depakote) may be associated with increased risk of autistic traits and/or [...] The post Prenatal Valproic Acid (Depakote) Exposure Increases Risk for Neurodevelopmental Disorders appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/32zvuEu via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

Early pregnancy loss (EPL) is common, affecting up to 25% of pregnancies.  Studies looking at the emotional consequences of miscarriage have shown that most women do well; however, some women experience clinically significant symptoms of depression and anxiety. In a previous study, Farren and colleagues prospectively examined the type and severity of emotional symptoms women [...] The post Impact of Miscarriage on Partners appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/2TVRWTb via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

Gabapentin (Neurontin) is now used in a wide variety of clinical settings — for the treatment of epilepsy, pain management, restless leg syndrome, anxiety, and sleep disturbance.  However, there is relatively little information regarding its reproductive safety.  We last reviewed this topic in 2015.  At that point, the literature included 333 cases of prenatal gabapentin [...] The post Study Supporting the Reproductive Safety of Gabapentin During Pregnancy appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/2HMySVd via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

St. John’s wort (Hypericum perforatum) is an herbal preparation which has been shown, in some studies, to be effective for the treatment of mild to moderate depressive symptoms. St. John’s wort is now one of the most commonly used herbal products in the United States and is widely used in Europe. We don’t know exactly [...] The post Is St. John’s Wort Effective for PMDD? appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/2TtSaRs via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

Modafinil (brand name Provigil) is a wake-promoting agent which is used to treat sleepiness due to narcolepsy, shift work sleep disorder, or obstructive sleep apnea.  It is also used in other settings, often in combination with other medications, to treat ADHD symptoms, depressive symptoms, and cognitive dysfunction.   In 2018, an interim report from a registry [...] The post New (But Still Not Enough) Data on Modafinil and Pregnancy appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/3kf6Qjf via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

While depression is relatively common in pregnancy and we have data to support the reproductive safety of many different antidepressants, many women are reluctant to use antidepressant medications during pregnancy. Because untreated depression in the mother has been associated with worse pregnancy outcomes and may have long term effects on the child, there is a [...] The post Transcranial Direct Current Stimulation for Depression during Pregnancy Shows Promising Results appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/2HgxvOj via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

Every week we review the most recent publications in women’s mental health, covering topics related to premenstrual symptoms, perinatal mood and anxiety disorders, use of medications in pregnant and breastfeeding women, perinatal substance use, and menopausal mental health.  Several articles focus on infertility and mental health.  Somewhat counterintuitively, a review article finds that infertile couples [...] The post Weekly Roundup for OCTOBER 9, 2020: Recent Publications in Women’s Mental Health appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/3730saN via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

While many women with postpartum depression (PPD) have had previous episodes of major depression and will go on to have other episodes of depression outside of the postpartum period, many have questioned whether postpartum depression represents a specific subtype of major depressive disorder (MDD), postulating that there may be characteristics which distinguish depression emerging during [...] The post Is Postpartum Depression a Distinct Subtype of Depression? Taking a Closer Look at the Amygdala appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/36CPWHj via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

Over the last few years, the medical community has been using the term perinatal mood and anxiety disorders (PMADs) to describe the spectrum of psychological symptoms women may experience during pregnancy or the postpartum period.  This shift reflects the realization that the term “postpartum depression” describes only the tip of a much larger iceberg; many [...] The post Measuring the Impact of Maternal Anxiety on Children’s Social-Emotional Development appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/3d4LpyD via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

Over the past seven months, the MGH Center for Women’s Mental Health has had the tremendous opportunity to host virtual rounds from 2-3pm EST via Zoom for all health professionals with an interest in reproductive psychiatry and women’s mental health. We have reached over 400 students and practitioners in 33 states, 3 Canadian provinces, [...] The post Virtual Rounds with CWMH Extended through July appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/2GBEHDW via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

Every week we review the most recent publications in women’s mental health, covering topics related to premenstrual symptoms, perinatal mood and anxiety disorders, use of medications in pregnant and breastfeeding women, perinatal substance use, and menopausal mental health.  We are seeing an increased number of articles looking at the impact of the COVID-19 pandemic on [...] The post Weekly Roundup for OCTOBER 3rd, 2020: Recent Publications in Women’s Mental Health appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/2GuUF2S via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

Although it is widely accepted that perimenopausal women are at increased risk for depressive symptoms, little research exploring suicidality in mid-life women has been conducted. In the spirit of Suicide Prevention Month, we will review here the risk of suicidality in midlife women and what factors may be at play in modulating this risk. Prior [...] The post Suicidality in Midlife Women: A Brief Overview appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/361RpXi via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

Every week we review the most recent publications in women’s mental health, covering topics related to premenstrual symptoms, perinatal mood and anxiety disorders, use of medications in pregnant and breastfeeding women, perinatal substance use, and menopausal mental health.  In a meta-analysis including nearly 200,000 mother-infant dyads, Rogers and colleagues look at the impact of perinatal [...] The post Weekly Roundup for SEPTEMBER 18, 2020: Recent Publications in Women’s Mental Health appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/35Yu3Sq via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

Women are at increased risk for depressive symptoms during the menopause transition.  It has long been suspected that falling estrogen levels play a role in triggering the onset of depression; however, if all women experience declining levels of estrogen and progesterone during this transition, why is it that only some women suffer from depression in [...] The post Perimenopausal Depression in Women with More Variable Levels of Estradiol and Lower Progesterone Levels appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/33vcl67 via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

While we have heard a lot about brexanolone, marketed by Sage Therapeutics as Zulresso, for the treatment of postpartum depression, an oral version of this novel antidepressant – SAGE 217 or zuranolone – has been finishing up its Phase 3 trials. Like brexanolone, SAGE-217 is a neuroactive steroid, an analogue of allopregnanolone which is a [...] The post More Data on the Neuroactive Steroid Zuranolone for Postpartum Depression appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/3bYaoDd via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

Every Wednesday, we have the pleasure of holding virtual rounds with other clinicians to discuss important topics in reproductive psychiatry.  So many great questions!  Last week, one of our participants asked about using light therapy for the treatment of depression during pregnancy.  This is a topic we haven’t covered for nearly a decade, so it [...] The post Can Bright Light Therapy Be Used for the Treatment of Depression During Pregnancy? appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/3m7qVZW via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

Perinatal psychiatry is a field in which we treat vulnerable patients, a mother and her child, where both the illness we are treating and the treatments we prescribe have the potential to affect the outcome.  There is a deep and compelling literature that describes the negative impact of postpartum depression upon children, and we are [...] The post Assessing the Reproductive Safety of Antidepressants: Can Non-Randomized Studies Provide the Information We Need? appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/2Z3dIaM via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

In March, when the COVID-19 pandemic hit Massachusetts, centers providing infertility services were forced to hit the pause button, leaving many couples in the United States in the lurch.  On March 17, the American Society of Reproductive Medicine (ASRM) issued guidelines for fertility specialists which consisted of five key recommendations, including the suspension of new [...] The post Fertility Treatment in the Midst of a Pandemic appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/2YXfb2r via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

Over the last few years we have heard a great deal about neurosteroids, also known as neuroactive steroids.  This class of compounds are steroid hormones produced in the brain and endocrine tissues which can modulate neurotransmission.  Animal studies have demonstrated that neurosteroids have a broad range of activities, including antidepressant, anxiolytic, sedative, analgesic, anticonvulsant, neuroprotective, [...] The post Pilot Study of Neurosteroid Ganaxolone for Menopausal Depression appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/2YWJOox via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/

Every week we review the most recent publications in women’s mental health, covering topics related to premenstrual symptoms, perinatal mood and anxiety disorders, use of medications in pregnant and breastfeeding women, perinatal substance use, and menopausal mental health.  For more detailed descriptions of many of these topics, you can sign up to receive our weekly [...] The post Weekly Roundup for AUGUST 28, 2020: Recent Publications in Women’s Mental Health appeared first on MGH Center for Women's Mental Health . from MGH Center for Women's Mental Health https://ift.tt/2Ev3WY1 via https://ift.tt/33YfKfD https://gani.vn/ #thucphamchucnanggani #gani.vn https://gani-blogvn.blogspot.com/ https://gani.vn/